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个人简历
工作经历
1997.7-至今 北京大学生命学院
杂志任职
2022-present，Guest editor，Plants
书籍编撰
李峰，王东辉译。加兰德∙E∙艾伦，杰弗里∙J.W.贝克著，《生命科学的历程》，中西书局，2020，出版书号：ISBN 978-7-5475-1735-2.
教材编撰
王东辉主编《植物发育生物学常用实验技术》北京:北京大学出版社, 2017，标准书号：ISBN 978-7-301-28202-1
科研领域描述
主要以水稻为对象，研究高等植物雄蕊发育过程的调控机理，并兼及其他课题。
代表性论文
一作或通讯作者：
[1]. 王东辉. 基于科研项目的实验教学探索与实践. 实验科学与技术，2024-0064（已接受）.
[2]. Wang DH#, Liu N, Ye SD, Chen ZH, Lin YN, Liu ZH, Xu ZH and Bai SN#. Rice tapetum differentiation is sensitive to downregulation of OsUCH3, a ubiquitin C-terminal hydrolase. Plant Biotechnology Journal, 2023,21(7):1314-1316.（#通讯作者）
[3]. 王璠麟,贺新强,王东辉#. 植物活体荧光分子影像系统的研制及其应用.北京大学学报(自然科学版), 2023, 10.13209/j.0479-8023.2023.019（#通讯作者）
[4]. 王东辉. 虚拟仿真和慕课共同助力植物学实验教学改革.高校生物学教学研究(电子版)，2022, 12 (6): 49-52.
[5]. 王东辉. 水稻整体原位杂交实验技术方法的改进.北京大学学报(自然科学版), 2022, 58(2):195-200.
[6]. 王东辉. 植物生长素整体原位定位技术.北京大学学报(自然科学版), 2022, 58(5): 795-800.
[7]. 王东辉#，王玄之，王梓豪，葛丽丽. 本科生植物学综合实验课程改革与实践.高校生物学教学研究(电子版)，2021,11(5):33-36 (#通讯作者).
[8]. Zheng Y*, Wang D*, Ye S, Chen W, Li G, Xu Z, Bai S, Zhao F. Auxin guides germ-cell specification in Arabidopsis anthers. PNAS USA, 2021,118(22):e2101492118.（*共同一作）（被专家在F1000上推介）
[9]. Hu DG*, Wang N*, Wang DH*, Cheng L, Wang YX, Zhao YW, Ding JY, Gu KD, Xiao X, Hao YJ. A basic/helix-loop-helix transcription factor controls leaf shape by regulating auxin signaling in apple. New Phytologist, 2020,228(6):1897-1913.（*共同一作）
[10]. Wang DH*, Song W*, Wei SW*, Zheng YF, Chen ZS, Han JD, Zhang HT, Luo JC, Qin YM, Xu ZH, Bai SN. Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa). Frontiers in Plant Science. 2018,9:1636.
[11]. Qi S*, Wang D*, Zhu L, Teng M, Wang C, Xue X, Wu L. Effects of a novel neonicotinoid insecticide cycloxaprid on earthworm, Eisenia fetida. Environmental Science and Pollution, 2018,25(14):14138-14147.（*共同一作）
[12]. Qi S*, Wang D*, Zhu L, Teng M, Wang C, Xue X, Wu L. Neonicotinoid insecticides imidacloprid, guadipyr, and cycloxaprid induce acute oxidative stress in Daphnia magna. Ecotoxicology and Environmental Safety, 2018,148:352-358.（*共同一作）
[13]. 王东辉.植物学专业研究生实验教学模式的创新与实践.高校生物学教学研究(电子版). 2017, 7(3):43-47.
[14]. Chen R*, Shen LP*, Wang DH*, Wang FG*, Zeng HY*, Chen ZS, Peng YB, Lin YN, Tang X, Deng MH, Yao N, Luo JC, Xu ZH, Bai SN. A Gene Expression Profiling of Early Rice Stamen Development that Reveals Inhibition of Photosynthetic Genes by OsMADS58. Molecular Plant, 2015,8(7):1069-89.（*共同一作）
[15]. Wang DH, Wang DQ, Cui YW, Yang L, Gu XL, Song WF, Li F. Photoperiod regulates Cape sundrew (Drosera capensis) gland sevretion and leaf development. Carnivorous Plant Newsletter,2015, 44(4):197-203.
[16]. Wang DH, Li F, Duan QH, Han T, Xu ZH, Bai SN. Ethylene perception is involved in female cucumber flower development. Plant Journal, 2010,61(5):862-72.
[17]. Hao YJ*, Wang DH*, Peng YB, Bai SL, Xu LY, Li YQ, Xu ZH, Bai SN. DNA damage in the early primordial anther is closely correlated with stamen arrest in the female flower of cucumber (Cucumis sativus L.). Planta, 2003,217(6):888-95.（*共同一作）
其他代表性论文：
[18]. Li F, Yang JJ, Sun ZY, Wang L, Qi LY, A S, Liu YQ, Zhang HM, Dang LF, Wang SJ, Luo CX, Nian WF, O`Conner S, Ju LZ, Quan WP, Li XK, Wang C, Wang DP, You HL, Cheng ZK, Yan J, Tang FC, Yang DC, Xia CW, Gao G, Wang Y, Zhang BC, Zhou YH, Guo X, Xiang SH, Liu H, Peng TB, Su XD, Chen Y, Ouyang Q, Wang DH, Zhang DM, Xu ZH, Hou HW, Bai SN, Li L. Plant-on-chip: Core morphogenesis processes in the tiny plant Wolffia australiana. PNAS Nexus. 2023,2(5): pgad141.
[19]. Wang S, Teng D, Li X, Yang P, Da W, Zhang Y, Zhang Y, Liu G, Zhang X, Wan W, Dong Z, Wang D, Huang S, Jiang Z, Wang Q, Lohman DJ, Wu Y, Zhang L, Jia F, Westerman E, Zhang L, Wang W, Zhang W. The evolution and diversification of oakleaf butterflies. Cell, 2022,185(17):3138-3152.e20.
[20]. Lin YN, Jiang CK, Cheng ZK, Wang DH, Shen LP, Xu C, Xu ZH, Bai SN. Rice Cell Division Cycle 20s are required for faithful chromosome segregation and cytokinesis during meiosis. Plant Physiology, 2022,188(2):1111-1128.
[21]. Shen L, Tian F, Cheng Z, Zhao Q, Feng Q, Zhao Y, Han B, Fang Y, Lin Y, Chen R, Wang D, Sun W, Sun J, Zeng H, Yao N, Gao G, Luo J, Xu Z, Bai S. OsMADS58 Stabilizes Gene Regulatory Circuits during Rice Stamen Development. Plants (Basel), 2022,11(21):2899.
[22]. Wang L, Hou J, Xu H, Zhang Y, Huang R, Wang D, He XQ. The PtoTCP20-miR396d-PtoGRF15 module regulates secondary vascular development in Populus. Plant Communication, 2022,23:100494.
[23]. Zhang H, Li S, Yang L, Cai G, Chen H, Gao D, Lin T, Cui Q, Wang D, Li Z, Cai R, Bai S, Lucas WJ, Huang S, Zhang Z, Sun J. Gain-of-function of the 1-aminocyclopropane-1-carboxylate synthase gene ACS1G induces female flower development in cucumber gynoecy. Plant Cell, 2021,33(2):306-321.
[24]. Yang Y, Chang J, Wang D, Ma H, Li Y, Zheng Y. Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio). Archives of Toxicology, 2021,95(12):3777-3786.
[25]. Yang Z, Huang Y, Yang J, Yao S, Zhao K, Wang D, Qin Q, Bian Z, Li Y, Lan Y, Zhou T, Wang H, Liu C, Wang W, Qi Y, Xu Z, Li Y. Jasmonate Signaling Enhances RNA Silencing and Antiviral Defense in Rice. Cell Host & Microbe, 2020,28(1):89-103.e8.
[26]. Qian L, Liu J, Lin Z, Chen X, Yuan L, Shen G, Yang W, Wang D, Huang Y, Pang S, Mu X, Wang C, Li Y. Evaluation of the spinal effects of phthalates in a zebrafish embryo assay. Chemosphere, 2020,249:126144.
[27]. Mu X, Chen X, Liu J, Yuan L, Wang D, Qian L, Qian Y, Shen G, Huang Y, Li X, Li Y, Lin X. A multi-omics approach reveals molecular mechanisms by which phthalates induce cardiac defects in zebrafish (Danio rerio). Environmental Pollution, 2020,265(Pt B):113876.
[28]. Qi S, Niu X, Wang DH, Wang C, Zhu L, Xue X, Zhang Z, Wu L. Flumethrin at sublethal concentrations induces stresses in adult honey bees (Apis mellifera L.). Science of the Total Environment, 2020,700:134500.
[29]. Yang Y, Dong F, Liu X, Xu J, Wu X, Wang D, Zheng Y. Developmental toxicity by thifluzamide in zebrafish (Danio rerio): Involvement of leptin. Chemosphere, 2019,221:863-869.
[30]. Chen ZS, Liu XF, Wang DH, Chen R, Zhang XL, Xu ZH, Bai SN. Transcription Factor OsTGA10 Is a Target of the MADS Protein OsMADS8 and Is Required for Tapetum Development. Plant Physiology, 2018,176(1):819-835.
[31]. Sha S, Chen D, Liu M, Li KL, Jiang CK, Wang DH, Guo YP. To be serrate or pinnate: diverse leaf forms of yarrows (Achillea) are linked to differential expression patterns of NAM genes. Annals of Botany, 2018,121(2):255-266.
[32]. Chen H, Sun J, Li S, Cui Q, Zhang H, Xin F, Wang H, Lin T, Gao D, Wang S, Li X, Wang D, Zhang Z, Xu Z, Huang S. An ACC Oxidase Gene Essential for Cucumber Carpel Development. Molecular Plant, 2016,9(9):1315-1327.
[33]. Sun JJ, Li F, Wang DH, Liu XF, Li X, Liu N, Gu HT, Zou C, Luo JC, He CX, Huang SW, Zhang XL, Xu ZH, Bai SN. CsAP3: A Cucumber Homolog to Arabidopsis APETALA3 with Novel Characteristics. Frontiers in Plant Science, 2016,7:1181
[34]. Li F, Sun J, Wang D, Bai S, Clarke AK, Holm M. The B-box family gene STO (BBX24) in Arabidopsis thaliana regulates flowering time in different pathways. PLoS One, 2014,9(2):e87544.
[35]. Gu HT, Wang DH, Li X, He CX, Xu ZH, Bai SN. Characterization of an ethylene-inducible, calcium-dependent nuclease that is differentially expressed in cucumber flower development. New Phytologist, 2011,192(3):590-600.
[36]. Sun JJ, Li F, Li X, Liu XC, Rao GY, Luo JC, Wang DH, Xu ZH, Bai SN. Why is ethylene involved in selective promotion of female flower development in cucumber? Plant Signal Behav, 2010,5(8):1052-6.
[37]. Duan QH, Wang DH, Xu ZH, Bai SN. Stamen development in Arabidopsis is arrested by organ-specific overexpression of a cucumber ethylene synthesis gene CsACO2. Planta, 2008,228(4):537-43.
[38]. Peng YB, Zou C, Wang DH, Gong HQ, Xu ZH, Bai SN. Preferential localization of abscisic acid in primordial and nursing cells of reproductive organs of Arabidopsis and cucumber. New Phytologist, 2006,170(3):459-66.
[39]. Gong HQ, Peng YB, Zou C, Wang DH, Xu ZH, Bai SN. A simple treatment to significantly increase signal specificity in immunohistochemistry. Plant Molecular Biolology Reports, 2006, 24: 93-101.
[40]. Zhao Y, Shi Y, Zhao W, Huang X, Wang D, Brown N, Brand J, Zhao J. CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation. PNAS USA, 2005,102(16):5744-8.
[41]. Gong W, Shen YP, Ma LG, Pan Y, Du YL, Wang DH, Yang JY, Hu LD, Liu XF, Dong CX, Ma L, Chen YH, Yang XY, Gao Y, Zhu D, Tan X, Mu JY, Zhang DB, Liu YL, Dinesh-Kumar SP, Li Y, Wang XP, Gu HY, Qu LJ, Bai SN, Lu YT, Li JY, Zhao JD, Zuo J, Huang H, Deng XW, Zhu YX. Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes. Plant Physiology, 2004,135(2):773-82.
[1]. 王东辉. 基于科研项目的实验教学探索与实践. 实验科学与技术，2024-0064（已接受）.
[2]. Wang DH#, Liu N, Ye SD, Chen ZH, Lin YN, Liu ZH, Xu ZH and Bai SN#. Rice tapetum differentiation is sensitive to downregulation of OsUCH3, a ubiquitin C-terminal hydrolase. Plant Biotechnology Journal, 2023,21(7):1314-1316.（#通讯作者）
[3]. 王璠麟,贺新强,王东辉#. 植物活体荧光分子影像系统的研制及其应用.北京大学学报(自然科学版), 2023, 10.13209/j.0479-8023.2023.019（#通讯作者）
[4]. 王东辉. 虚拟仿真和慕课共同助力植物学实验教学改革.高校生物学教学研究(电子版)，2022, 12 (6): 49-52.
[5]. 王东辉. 水稻整体原位杂交实验技术方法的改进.北京大学学报(自然科学版), 2022, 58(2):195-200.
[6]. 王东辉. 植物生长素整体原位定位技术.北京大学学报(自然科学版), 2022, 58(5): 795-800.
[7]. 王东辉#，王玄之，王梓豪，葛丽丽. 本科生植物学综合实验课程改革与实践.高校生物学教学研究(电子版)，2021,11(5):33-36 (#通讯作者).
[8]. Zheng Y*, Wang D*, Ye S, Chen W, Li G, Xu Z, Bai S, Zhao F. Auxin guides germ-cell specification in Arabidopsis anthers. PNAS USA, 2021,118(22):e2101492118.（*共同一作）（被专家在F1000上推介）
[9]. Hu DG*, Wang N*, Wang DH*, Cheng L, Wang YX, Zhao YW, Ding JY, Gu KD, Xiao X, Hao YJ. A basic/helix-loop-helix transcription factor controls leaf shape by regulating auxin signaling in apple. New Phytologist, 2020,228(6):1897-1913.（*共同一作）
[10]. Wang DH*, Song W*, Wei SW*, Zheng YF, Chen ZS, Han JD, Zhang HT, Luo JC, Qin YM, Xu ZH, Bai SN. Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa). Frontiers in Plant Science. 2018,9:1636.
[11]. Qi S*, Wang D*, Zhu L, Teng M, Wang C, Xue X, Wu L. Effects of a novel neonicotinoid insecticide cycloxaprid on earthworm, Eisenia fetida. Environmental Science and Pollution, 2018,25(14):14138-14147.（*共同一作）
[12]. Qi S*, Wang D*, Zhu L, Teng M, Wang C, Xue X, Wu L. Neonicotinoid insecticides imidacloprid, guadipyr, and cycloxaprid induce acute oxidative stress in Daphnia magna. Ecotoxicology and Environmental Safety, 2018,148:352-358.（*共同一作）
[13]. 王东辉.植物学专业研究生实验教学模式的创新与实践.高校生物学教学研究(电子版). 2017, 7(3):43-47.
[14]. Chen R*, Shen LP*, Wang DH*, Wang FG*, Zeng HY*, Chen ZS, Peng YB, Lin YN, Tang X, Deng MH, Yao N, Luo JC, Xu ZH, Bai SN. A Gene Expression Profiling of Early Rice Stamen Development that Reveals Inhibition of Photosynthetic Genes by OsMADS58. Molecular Plant, 2015,8(7):1069-89.（*共同一作）
[15]. Wang DH, Wang DQ, Cui YW, Yang L, Gu XL, Song WF, Li F. Photoperiod regulates Cape sundrew (Drosera capensis) gland sevretion and leaf development. Carnivorous Plant Newsletter,2015, 44(4):197-203.
[16]. Wang DH, Li F, Duan QH, Han T, Xu ZH, Bai SN. Ethylene perception is involved in female cucumber flower development. Plant Journal, 2010,61(5):862-72.
[17]. Hao YJ*, Wang DH*, Peng YB, Bai SL, Xu LY, Li YQ, Xu ZH, Bai SN. DNA damage in the early primordial anther is closely correlated with stamen arrest in the female flower of cucumber (Cucumis sativus L.). Planta, 2003,217(6):888-95.（*共同一作）
其他代表性论文：
[18]. Li F, Yang JJ, Sun ZY, Wang L, Qi LY, A S, Liu YQ, Zhang HM, Dang LF, Wang SJ, Luo CX, Nian WF, O`Conner S, Ju LZ, Quan WP, Li XK, Wang C, Wang DP, You HL, Cheng ZK, Yan J, Tang FC, Yang DC, Xia CW, Gao G, Wang Y, Zhang BC, Zhou YH, Guo X, Xiang SH, Liu H, Peng TB, Su XD, Chen Y, Ouyang Q, Wang DH, Zhang DM, Xu ZH, Hou HW, Bai SN, Li L. Plant-on-chip: Core morphogenesis processes in the tiny plant Wolffia australiana. PNAS Nexus. 2023,2(5): pgad141.
[19]. Wang S, Teng D, Li X, Yang P, Da W, Zhang Y, Zhang Y, Liu G, Zhang X, Wan W, Dong Z, Wang D, Huang S, Jiang Z, Wang Q, Lohman DJ, Wu Y, Zhang L, Jia F, Westerman E, Zhang L, Wang W, Zhang W. The evolution and diversification of oakleaf butterflies. Cell, 2022,185(17):3138-3152.e20.
[20]. Lin YN, Jiang CK, Cheng ZK, Wang DH, Shen LP, Xu C, Xu ZH, Bai SN. Rice Cell Division Cycle 20s are required for faithful chromosome segregation and cytokinesis during meiosis. Plant Physiology, 2022,188(2):1111-1128.
[21]. Shen L, Tian F, Cheng Z, Zhao Q, Feng Q, Zhao Y, Han B, Fang Y, Lin Y, Chen R, Wang D, Sun W, Sun J, Zeng H, Yao N, Gao G, Luo J, Xu Z, Bai S. OsMADS58 Stabilizes Gene Regulatory Circuits during Rice Stamen Development. Plants (Basel), 2022,11(21):2899.
[22]. Wang L, Hou J, Xu H, Zhang Y, Huang R, Wang D, He XQ. The PtoTCP20-miR396d-PtoGRF15 module regulates secondary vascular development in Populus. Plant Communication, 2022,23:100494.
[23]. Zhang H, Li S, Yang L, Cai G, Chen H, Gao D, Lin T, Cui Q, Wang D, Li Z, Cai R, Bai S, Lucas WJ, Huang S, Zhang Z, Sun J. Gain-of-function of the 1-aminocyclopropane-1-carboxylate synthase gene ACS1G induces female flower development in cucumber gynoecy. Plant Cell, 2021,33(2):306-321.
[24]. Yang Y, Chang J, Wang D, Ma H, Li Y, Zheng Y. Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio). Archives of Toxicology, 2021,95(12):3777-3786.
[25]. Yang Z, Huang Y, Yang J, Yao S, Zhao K, Wang D, Qin Q, Bian Z, Li Y, Lan Y, Zhou T, Wang H, Liu C, Wang W, Qi Y, Xu Z, Li Y. Jasmonate Signaling Enhances RNA Silencing and Antiviral Defense in Rice. Cell Host & Microbe, 2020,28(1):89-103.e8.
[26]. Qian L, Liu J, Lin Z, Chen X, Yuan L, Shen G, Yang W, Wang D, Huang Y, Pang S, Mu X, Wang C, Li Y. Evaluation of the spinal effects of phthalates in a zebrafish embryo assay. Chemosphere, 2020,249:126144.
[27]. Mu X, Chen X, Liu J, Yuan L, Wang D, Qian L, Qian Y, Shen G, Huang Y, Li X, Li Y, Lin X. A multi-omics approach reveals molecular mechanisms by which phthalates induce cardiac defects in zebrafish (Danio rerio). Environmental Pollution, 2020,265(Pt B):113876.
[28]. Qi S, Niu X, Wang DH, Wang C, Zhu L, Xue X, Zhang Z, Wu L. Flumethrin at sublethal concentrations induces stresses in adult honey bees (Apis mellifera L.). Science of the Total Environment, 2020,700:134500.
[29]. Yang Y, Dong F, Liu X, Xu J, Wu X, Wang D, Zheng Y. Developmental toxicity by thifluzamide in zebrafish (Danio rerio): Involvement of leptin. Chemosphere, 2019,221:863-869.
[30]. Chen ZS, Liu XF, Wang DH, Chen R, Zhang XL, Xu ZH, Bai SN. Transcription Factor OsTGA10 Is a Target of the MADS Protein OsMADS8 and Is Required for Tapetum Development. Plant Physiology, 2018,176(1):819-835.
[31]. Sha S, Chen D, Liu M, Li KL, Jiang CK, Wang DH, Guo YP. To be serrate or pinnate: diverse leaf forms of yarrows (Achillea) are linked to differential expression patterns of NAM genes. Annals of Botany, 2018,121(2):255-266.
[32]. Chen H, Sun J, Li S, Cui Q, Zhang H, Xin F, Wang H, Lin T, Gao D, Wang S, Li X, Wang D, Zhang Z, Xu Z, Huang S. An ACC Oxidase Gene Essential for Cucumber Carpel Development. Molecular Plant, 2016,9(9):1315-1327.
[33]. Sun JJ, Li F, Wang DH, Liu XF, Li X, Liu N, Gu HT, Zou C, Luo JC, He CX, Huang SW, Zhang XL, Xu ZH, Bai SN. CsAP3: A Cucumber Homolog to Arabidopsis APETALA3 with Novel Characteristics. Frontiers in Plant Science, 2016,7:1181
[34]. Li F, Sun J, Wang D, Bai S, Clarke AK, Holm M. The B-box family gene STO (BBX24) in Arabidopsis thaliana regulates flowering time in different pathways. PLoS One, 2014,9(2):e87544.
[35]. Gu HT, Wang DH, Li X, He CX, Xu ZH, Bai SN. Characterization of an ethylene-inducible, calcium-dependent nuclease that is differentially expressed in cucumber flower development. New Phytologist, 2011,192(3):590-600.
[36]. Sun JJ, Li F, Li X, Liu XC, Rao GY, Luo JC, Wang DH, Xu ZH, Bai SN. Why is ethylene involved in selective promotion of female flower development in cucumber? Plant Signal Behav, 2010,5(8):1052-6.
[37]. Duan QH, Wang DH, Xu ZH, Bai SN. Stamen development in Arabidopsis is arrested by organ-specific overexpression of a cucumber ethylene synthesis gene CsACO2. Planta, 2008,228(4):537-43.
[38]. Peng YB, Zou C, Wang DH, Gong HQ, Xu ZH, Bai SN. Preferential localization of abscisic acid in primordial and nursing cells of reproductive organs of Arabidopsis and cucumber. New Phytologist, 2006,170(3):459-66.
[39]. Gong HQ, Peng YB, Zou C, Wang DH, Xu ZH, Bai SN. A simple treatment to significantly increase signal specificity in immunohistochemistry. Plant Molecular Biolology Reports, 2006, 24: 93-101.
[40]. Zhao Y, Shi Y, Zhao W, Huang X, Wang D, Brown N, Brand J, Zhao J. CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation. PNAS USA, 2005,102(16):5744-8.
[41]. Gong W, Shen YP, Ma LG, Pan Y, Du YL, Wang DH, Yang JY, Hu LD, Liu XF, Dong CX, Ma L, Chen YH, Yang XY, Gao Y, Zhu D, Tan X, Mu JY, Zhang DB, Liu YL, Dinesh-Kumar SP, Li Y, Wang XP, Gu HY, Qu LJ, Bai SN, Lu YT, Li JY, Zhao JD, Zuo J, Huang H, Deng XW, Zhu YX. Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes. Plant Physiology, 2004,135(2):773-82.
