生命科学联合中心学术报告

题目：Synthetic Chemistry for Epigenetic Modification Studies

报告人：Akimitsu Okamoto, Ph.D.

Professor

Research Center for Advanced Science and Technology (RCAST)

The University of Tokyo

时间：2016-5-12（周四），13:00-14:00pm

地点：北京大学金光生命科学大楼101报告厅

联系人：伊成器  北大-清华生命科学联合中心

The development of chemical reactions for the detection of epigenetic modifications in a cell is a chemically and biologically challenging research subject. I will talk about (1) a 5-methylcytosine imaging through the formation of 5-methylcytosine-osmium complexes; (2) new chemical reactions for detection of 5-hydroxymethylcytosine; (3) exciton-controlled hybridization-sensitive fluorescent oligonucleotide probes for RNA imaging; (4) photoaffinity-labeled RNA for trapping FTO demethylase; and (5) chemical synthesis of modified histone H2A.

欢迎各位老师同学积极参加！