北京大学 | ENGLISH
讲座信息
Nutrient Sensing and metabolic communication
发布时间:2015-12-01      点击量:1369
主讲人:Xiaoyong Yang
讲座地点:北京大学邓祐才报告厅
讲座日期:2015-12-07
讲座时间:13:00 — 14:30
联系人:陈兴
 

生命科学联合中心学术报告

题目:Nutrient Sensing and metabolic communication.

报告人:Xiaoyong Yang, Ph.D.

Associate Professor

Section of Comparative Medicine and Department of Cellular and Molecular Physiology,

Yale University School of Medicine

时间:2015-12-7(周一),13:00-14:30pm

地点:北京大学邓祐才报告厅

联系人:陈兴 北大-清华生命科学联合中心

Nuclear, cytoplasmic, and mitochondrial proteins are extensively modified by O-linked β-N-acetylglucosamine (O-GlcNAc) moieties. This sugar modification regulates fundamental cellular processes in response to diverse nutritional and hormonal cues. The enzymes O-GlcNAc transferase (OGT) and O-linked b-N acetylglucosaminase (O-GlcNAcase) mediate the addition and removal of O-GlcNAc, respectively. Because aberrant O-GlcNAcylation has broad implications in obesity and diabetes, unraveling the role of O-GlcNAc in metabolic regulation is of emerging importance. I will present our recent discoveries on the roles of protein O-GlcNAcylation in nutrient sensing and metabolic communication between the brain and adipose tissue.

欢迎各位老师同学积极参加!

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