生命科学联合中心学术报告

题目：Developing New Covalent Inhibitors to Treat Cancer.

报告人：Nathanael Gray, Ph.D.

Professor of Biological Chemistry and Molecular Pharmacology

Harvard Medical School

Cancer Biology at Dana Farber

时间：2015-6-4（周四），13:00-14:00pm

地点：北京大学邓祐才报告厅

联系人：雷晓光

Despite the tremendous increase in understanding of basic cancer mechanisms and potential targets there has only been a moderate increase in effective new therapies to treat cancer.  With the ever growing costs of bringing new drugs to market, there is increasing conservatism in what is considered a promising new target to develop drugs against. The primary focus of the Gray lab is to develop inhibitors for wild-type and mutant forms of protein kinases that can be used for pharmacological validation experiments.

The lecture will discuss new chemical biology and medicinal approaches to developing prototype drugs to treat cancer. The lecture will provide an overview of kinase targeting strategies and focus on efforts to develop the first covalent inhibitors of Cdk7, Her3 and K-RAS.

欢迎各位老师同学积极参加！